From the Blog

Ligand binding assays

Our discussions of various bioanalytical methodologies over the past few weeks has focused on chromatography and small molecule analysis. Today we are going to discuss a collection of methods that is commonly used for large molecules, such as peptides, peptides and macromolecules. These molecules are often called “biologics” because they are generally derived from endogenous […]

Understanding LC/MS/MS

The most common bioanalytical method in use today is LC/MS/MS, or liquid chromatography (LC) tandem mass spectrometry (MS). This is a very versatile, robust, and sensitive methodology that is used for nearly all small molecules. In addition, this technology is amenable to automation and un-attended analysis. The LC/MS/MS methodology is very similar to HPLC/UV, which […]

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