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From the Blog

Tips for custom IVIVC models in Phoenix

Author: Simon Davis Original Poster Link The IVIVC tool within Phoenix is a convenient and powerful tool to build an in vivo-invitro correlation model using dissolution experiments and real in vivo profiles.  This module can support your organisation in formulation development and even in applying for Biowaivers. The tool has a flexible library of built-in models […]

How Biosimulation is Changing Drug Development

PK/PD modeling and simulation is a part of a larger science called biosimulation, and it is changing drug development. We are using complex models to simulate clinical responses that help us develop medicines more rapidly and with greater safety. Check out this short video on how Certara is leading this biosimulation effort.   Disclaimer: This […]

Derivation for logarithmic trapezoidal AUC calculation

Calculating area under the curve requires the use of two separate equations: one is follows the “linear trapezoidal rule” and the other follows the “logarithmic trapezoidal rule”. These equations are normally presented in textbooks without derivations so all you have to to is insert the concentrations and times and you can calculate the area under […]

PK/PD Modeling Methodology Training – Dan Weiner

Phoenix NLME Training – Nathan Teuscher